YchF-GTPase C terminal protein domain

In molecular biology, this protein domain is found at the C terminus of the GTP-binding protein, YchF-GTPase found in both prokaryotes and eukaryotes.

C terminal domain of YchF-GTPase
ychf protein (hi0393)
Identifiers
Symbol	YchF-GTPase_C
Pfam	PF06071
Pfam clan	CL0072
InterPro	IPR013029
SCOP2	1ni3 / SCOPe / SUPFAM
CDD	cd04867
Available protein structures: Pfam   structures / ECOD   PDB RCSB PDB; PDBe; PDBj PDBsum structure summary

Function

The function of this protein domain remains unknown, however, it is putatively thought to be necessary for ribosome function or for signal transduction from the ribosome to downstream targets. Additionally, GTPases are often described as a molecular switch.^[1]

Structure

The crystal structure of Haemophilus influenzae has been determined.^[2] This protein consists of three domains, of which the C-terminal domain which is composed of a six-stranded half-barrel curved around an alpha helix.