ZC-B

ZC-B (3-(4-bromo-2,5-dimethoxyphenyl)azetidine) is a phenethylamine derivative which acts as a serotonin receptor agonist selective for the 5-HT₂ subtypes, with an EC₅₀ of 1.6nM at 5-HT_2A, vs 5.8nM at 5-HT_2C. It is structurally related to the psychedelic phenethylamines 2C-B and DOB, but with the amine side chain conformationally restricted as an azetidine ring.^[1][2]

ZC-B

Identifiers
IUPAC name 3-(4-bromo-2,5-dimethoxyphenyl)azetidine
CAS Number	2641630-65-9
PubChem CID	156337249
UNII	9EP4MV3URL
Chemical and physical data
Formula	C11H14BrNO2
Molar mass	272.142 g·mol−1
3D model (JSmol)	Interactive image
SMILES COC1=CC(=C(C=C1C2CNC2)OC)Br
InChI InChI=1S/C11H14BrNO2/c1-14-10-4-9(12)11(15-2)3-8(10)7-5-13-6-7/h3-4,7,13H,5-6H2,1-2H3 Key:YFCASESLVDHSAW-UHFFFAOYSA-N

See also

• Cyclized phenethylamine
• DOB
• β-Methyl-2C-B
• 2C-B-PYR
• 4C-B
• TCB-2
• LPH-5
• LSZ