Zolantidine

Zolantidine is a brain-penetrating selective histamine H₂ receptor (HRH₂) antagonist developed by Smith, Kline & French, with the research code of SK&F 95282. It is a benzothiazole derivative with a 30-fold higher potency for H₂ receptors than other peripheral and central receptors.^[1]

Zolantidine

Clinical data
ATC code	None
Identifiers
IUPAC name N-[3-[3-(piperidin-1-ylmethyl)phenoxy]propyl]-1,3-benzothiazol-2-amine
CAS Number	104076-38-2
PubChem CID	91769
ChemSpider	82866
UNII	M1108XAY01
ChEMBL	ChEMBL419296
CompTox Dashboard (EPA)	DTXSID6048460
Chemical and physical data
Formula	C22H27N3OS
Molar mass	381.54 g·mol−1
3D model (JSmol)	Interactive image
SMILES n1c4ccccc4sc1NCCCOc2cc(ccc2)CN3CCCCC3
InChI InChI=1S/C22H27N3OS/c1-4-13-25(14-5-1)17-18-8-6-9-19(16-18)26-15-7-12-23-22-24-20-10-2-3-11-21(20)27-22/h2-3,6,8-11,16H,1,4-5,7,12-15,17H2,(H,23,24) Key:KUBONGDXTUOOLM-UHFFFAOYSA-N