PIK3R3

La subunidad reguladora gamma de la fosfatidilinositol 3-quinasa (PIK3R3) es una enzima codificada en humanos por el gen PIK3R3.^[3][4]

PIK3R3
Identificadores
Alias	PIK3R3, p55, p55-GAMMA, p55PIK, phosphoinositide-3-kinase regulatory subunit 3, PI3KR3
IDs externos	OMIM: 606076 MGI: 109277 HomoloGene: 2690 GeneCards: PIK3R3
Ontología génica Función molecular • phosphatidylinositol 3-kinase regulator activity • GO:0001948, GO:0016582 unión a proteína plasmática • 1-phosphatidylinositol-3-kinase activity • phosphotyrosine residue binding • 1-phosphatidylinositol-3-kinase regulator activity Componente celular • citosol • phosphatidylinositol 3-kinase complex Proceso biológico • regulation of phosphatidylinositol 3-kinase activity • phosphatidylinositol-3-phosphate biosynthetic process • GO:1901047 insulin receptor signaling pathway • positive regulation of protein phosphorylation • cell migration involved in sprouting angiogenesis • GO:1901313 positive regulation of gene expression • protein kinase B signaling • positive regulation of cell migration • phosphatidylinositol phosphate biosynthetic process • phosphatidylinositol biosynthetic process Fuentes: Amigo / QuickGO
Patrón de la expressión del ARN
Más referencias a datos de expressión
Ortólogos
Especies	Humano	Ratón
Entrez	8503	18710
Ensembl	ENSG00000117461	ENSMUSG00000028698
UniProt	Q92569	Q64143
SeqRef (ARNm)	NM_001114172 NM_001303428 NM_001303429 NM_001328648 NM_001328649 NM_001328650 NM_001328651 NM_001328652 NM_001328653 NM_001328654 NM_003629	NM_181585 NM_001355584 NM_001355585 NM_001355586
SeqRef (proteina)	NP_001107644 NP_001290357 NP_001290358 NP_001315577 NP_001315578 NP_001315579 NP_001315580 NP_001315581 NP_001315582 NP_001315583 NP_003620	NP_853616 NP_001342513 NP_001342514 NP_001342515
Localización (UCSC)	n/a	n/a
Búsqueda en PubMed	[1]	[2]
Wikidata
Ver/Editar Humano		Ver/Editar Ratón

Interacciones

La proteína PIK3R3 ha demostrado ser capaz de interaccionar con:

• IGF1R^[5]
• IRS1^[6][5]
• Proteína del retinoblastoma^[7]