SDHC

SDHC merupakan berkas genetik pada kromosom 1 lokasi 1q23.3 dengan ekspresi genetik berupa protein cybL yang merupakan sub-unit C dari suksinat dehidrogenase. Mutasi pada gen ini mengakibatkan paraganglioma.^[4]

SDHC
Pengidentifikasi
Alias	SDHC, CYB560, CYBL, PGL3, QPS1, SDH3, succinate dehydrogenase complex subunit C
ID eksternal	OMIM: 602413 MGI: 1913302 HomoloGene: 2256 GeneCards: SDHC
Lokasi gen (Tikus) Kr. Kromosom 1 (tikus)[1] Pita 1|1 H3 Awal 170,954,734 bp[1] Akhir 170,978,172 bp[1]
Ontologi gen Fungsi molekuler • electron transfer activity • oxidoreductase activity, acting on the CH-CH group of donors • succinate dehydrogenase activity • heme binding • metal ion binding • succinate dehydrogenase (ubiquinone) activity • ubiquinone binding Komponen seluler • komponen integral membran • mitochondrial inner membrane • respiratory chain complex II • succinate dehydrogenase complex • mitokondria • membran • mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) Proses biologis • aerobic respiration • Siklus asam sitrat • mitochondrial electron transport, succinate to ubiquinone • GO:0001306 response to oxidative stress Sumber:Amigo / QuickGO
Ortolog
Spesies	Manusia	Tikus
Entrez	6391	66052
Ensembl	ENSG00000143252	ENSMUSG00000058076
UniProt	Q99643	Q9CZB0
RefSeq (mRNA)	NM_001035511 NM_001035512 NM_001035513 NM_001278172 NM_003001	NM_025321
RefSeq (protein)	NP_001030588 NP_001030589 NP_001030590 NP_001265101 NP_002992	NP_079597
Lokasi (UCSC)	n/a	Chr 1: 170.95 – 170.98 Mb
Pencarian PubMed	[2]	[3]
Wikidata
Lihat/Sunting Manusia Lihat/Sunting Tikus