| Jaar | Baan | Winnaar | Score | Info |
| Houston Open |
| 1946 | River Oaks Country Club |  Byron Nelson | 274 | –10 | |
| 1947 | Memorial Park Golf Course |  Bobby Locke | 277 | –11 | |
| 1948 | Geen toernooi |
| 1949 | Pine Forest Country Club | Johnny Palmer | 272 | –16 | |
| 1950 | BraeBurn Country Club | Cary Middlecoff | 277 | –11 | |
| 1951 | Memorial Park Golf Course | Marty Furgol | 277 | –11 | |
| 1952 | Memorial Park Golf Course | Jack Burke jr. | 277 | –11 | |
| 1953 | Memorial Park Golf Course | Cary Middlecoff po | 283 | –5 | Won de play-off van Jim Ferrier & Shelley Mayfield |
| 1954 | Memorial Park Golf Course | Dave Douglas | 277 | –11 | |
| 1955 | Memorial Park Golf Course | Mike Souchak | 273 | –15 | |
| 1956 | Memorial Park Golf Course | Ted Kroll | 277 | –11 | |
| 1957 | Memorial Park Golf Course | Arnold Palmer | 279 | –9 | |
| 1958 | Memorial Park Golf Course | Ed Oliver | 281 | –7 | |
| Houston Classic |
| 1959 | Memorial Park Golf Course | Jack Burke jr. po | 277 | –11 | Won de play-off van Julius Boros |
| 1960 | Memorial Park Golf Course | Bill Collins po | 280 | –8 | Won de play-off van Arnold Palmer |
| 1961 | Memorial Park Golf Course | Jay Hebert po | 276 | –4 | Won de play-off van Ken Venturi |
| 1962 | Memorial Park Golf Course | Bobby Nichols po | 278 | –2 | Won de play-off van Jack Nickalus en Dan Sikes |
| 1963 | Memorial Park Golf Course |  Bob Charles | 268 | –12 | |
| 1964 | Sharpstown Park Golf Course | Mike Souchak | 278 | –6 | |
| 1965 | Sharpstown Park Golf Course | Bobby Nichols | 273 | –11 | |
| Houston Champions International |
| 1966 | Champions Golf Club | Arnold Palmer | 275 | –9 | |
| 1967 | Champions Golf Club | Frank Beard | 274 | –10 | |
| 1968 | Champions Golf Club |  Roberto De Vicenzo | 274 | –10 | |
| 1969 | Geen toernooi want de club ontving het US Open |
| 1970 | Champions Golf Club | Gibby Gilbert po | 282 | –2 | Won de play-off van Bruce Crampton |
| 1971 | Champions Golf Club | Hubert Green po | 280 | –4 | Won de play-off van Don January |
| Houston Open |
| 1972 | Westwood Country Club |  Bruce Devlin | 278 | –10 | |
| 1973 | Quail Valley Golf Course | Bruce Crampton | 277 | –11 | |
| 1974 | Quail Valley Golf Course | Dave Hill | 276 | –12 | |
| 1975 | The Woodlands Country Club | Bruce Crampton | 273 | –15 | |
| 1976 | The Woodlands Country Club | Lee Elder | 278 | –10 | |
| 1977 | The Woodlands Country Club | Gene Littler | 276 | –12 | |
| 1978 | The Woodlands Country Club | Gary Player | 270 | –18 | |
| 1979 | The Woodlands Country Club | Wayne Levi | 268 | –16 | |
| Michelob-Houston Open |
| 1980 | The Woodlands Country Club | Curtis Strange po | 266 | –18 | Won de play-off van Lee Trevino |
| 1981 | The Woodlands Country Club | Ron Streck | 198 | –15 | Wegens slechte weer, afgewerkt in 3 ronden |
| 1982 | The Woodlands Country Club | Ed Sneed | 275 | –9 | |
| Houston Coca-Cola Open |
| 1983 | The Woodlands Country Club | David Graham | 275 | –9 | |
| 1984 | The Woodlands Country Club | Corey Pavin po | 274 | –10 | Won de play-off van Calvin Peete |
| Houston Open |
| 1985 | TPC The Woodlands | Raymond Floyd | 277 | –11 | |
| 1986 | TPC The Woodlands | Curtis Strange | 274 | –14 | |
| 1987 | TPC The Woodlands | Jay Haas po | 276 | –12 | Won de play-off van Buddy Gardner |
| Independent Insurance Agent Open |
| 1988 | TPC The Woodlands | Curtis Strange po | 270 | –18 | Won de play-off van Greg Norman |
| 1989 | TPC The Woodlands | Mike Sullivan | 280 | –8 | |
| 1990 | TPC The Woodlands | Tony Sills | 204 | –12 | |
| 1991 | TPC The Woodlands | Fulton Allem | 273 | –15 | |
| Shell Houston Open |
| 1992 | TPC The Woodlands | Fred Funk | 272 | –16 | |
| 1993 | TPC The Woodlands | Jim McGovern | 199 | –17 | Wegens slechte weer, afgewerkt in 3 ronden |
| 1994 | TPC The Woodlands | Mike Heinen | 272 | –16 | |
| 1995 | TPC The Woodlands | Payne Stewart po | 276 | –12 | Won de play-off van Scott Hoch |
| 1996 | TPC The Woodlands | Mark Brooks po | 274 | –14 | Won de play-off van Jeff Maggert |
| 1997 | TPC The Woodlands | Phil Blackmar po | 276 | –12 | Won de play-off van Kevin Sutherland |
| 1998 | TPC The Woodlands | David Duval | 276 | –12 | |
| 1999 | TPC The Woodlands | Stuart Appleby | 279 | –9 | |
| 2000 | TPC The Woodlands | Robert Allenby po | 275 | –13 | Won de play-off van Craig Stadler |
| 2001 | TPC The Woodlands | Hal Sutton | 278 | –10 | |
| 2002 | TPC The Woodlands |  Vijay Singh | 266 | –22 | |
| 2003 | Redstone Golf Club | Fred Couples | 267 | –21 | |
| 2004 | Redstone Golf Club | Vijay Singh | 277 | –11 | |
| 2005 | Redstone Golf Club | Vijay Singh po | 275 | –13 | Won de play-off van John Daly |
| 2006 | Redstone Golf Club | Stuart Appleby | 269 | –19 | |
| 2007 | Redstone Golf Club | Adam Scott | 271 | –17 | |
| 2008 | Redstone Golf Club | Johnson Wagner | 272 | –16 | |
| 2009 | Redstone Golf Club |  Paul Casey po | 277 | –11 | Won de play-off van J.B. Holmes |
| 2010 | Redstone Golf Club | Anthony Kim po | 276 | –12 | Won de play-off van Vaughn Taylor |
| 2011 | Redstone Golf Club | Phil Mickelson | 268 | –20 | |
| 2012 | Redstone Golf Club | Hunter Mahan | 272 | –16 | |
| 2013 | Redstone Golf Club | D A Points | 272 | –16 | |
| 2014 | Golf Club of Houston | Matt Jones po | 273 | –15 | Won de play-off van Matt Kuchar |
| 2015 | Golf Club of Houston | J.B. Holmes po | 272 | –16 | Won de play-off van Johnson Wagner en Jordan Spieth |
| 2016 | Golf Club of Houston | Jim Herman | 273 | –15 | Eerste zege op de PGA Tour voor Jim Herman |
Voor het gelijkaardige golftoernooi die opgericht werd in 1922, zie Houston Open (vroegere PGA Tour).
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