Prêmio Cameron de Terapêutica da Universidade de Edimburgo

O Prêmio Cameron de Terapêutica da Universidade de Edimburgo (em inglês: Cameron Prize for Therapeutics of the University of Edinburgh) é concedido pelo College of Medicine and Veterinary Medicine da Universidade de Edimburgo a uma personalidade que realizou uma contribuição de alta importância e valor à prática terapêutica nos últimos cinco anos. O prêmio foi estabelecido em 1878 pelo Dr. Andrew Robertson Cameron of Richmond, New South Wales, com uma soma de £ 2.000. O senatus academicus da universidade pode requerer do ganhador do prêmio apresentar uma ou mais palestras ou publicar um texto sobre a adição feita à prática terapêutica.^[1]

Recipientes

Data	Recipiente	Instituição	Campo de interesse
1879	Paul Bert	Faculdade de Ciências, Sorbonne, Paris	Doença de descompressão, toxicidade de altas concentrações de oxigênio
1880	William Roberts	Owens College, Manchester	Descobriu os efeitos antibacterianos dos fungos penicillium, cunhou a palavra "enzima"
1889	Louis Pasteur	Instituto Pasteur	Princípios de vacinação, primeiras vacinas para raiva e antraz, fermentação microbiana, pasteurização, primeira resolução de isômeros ópticos
1890	Joseph Lister	King's College Hospital, London	Pioneiro da cirurgia anti-séptica
1891	David Ferrier	King's College Hospital, London	Localização cortical[2]
1893	Victor Horsley	National Hospital for Neurology and Neurosurgery	Desenvolveu o aparelho de Horsley-Clarke, neurocirurgia estereotáxica, epilepsia
1894	Emil Adolf von Behring	Marburg University, Marburg, Germany	Soro para difteria
1896	William Macewen	University of Glasgow	Procedimentos assépticos na sala de operações, pioneiro em cirurgia cerebral e para o desenvolvimento de várias técnicas e procedimentos operacionais bem-sucedidas em cirurgia óssea
1897	Thomas R Fraser	Department of Materia Medica Edinburgh	Introduziu estrofanto e fisostigmina
1898	Sydney Copeman	Ministry of Health. UK	Autoridade em vacinação
1899	David Bruce	Army Medical School at Netley, UK	Brucelose e tripanossomas investigados, identificando a causa da doença do sono
1900	Waldemar Haffkine	Instituto Pasteur em Paris	Vacinas contra cólera e peste bubônica
1901	Patrick Manson	The London School of Hygiene & Tropical Medicine	Descobertas em parasitologia e fundador do campo da medicina tropical
1902	Ronald Ross	University College, Liverpool, United Kingdom	Malária, pela qual mostrou como ela entra no organismo. Ganhou o Prêmio Nobel em 1902
1904	Niels Ryberg Finsen	Copenhagen University Hospital	Tratamento do lúpus vulgar com radiação luminosa concentrada. Ganhou o Prêmio Nobel em 1903
1910	August Karl Gustav Bier	Charité - Universitätsmedizin, Berlin	Anestesia espinhal com cocaína e anestesia regional intravenosa
1911	Simon Flexner	Rockefeller Institute for Medical Research	Estudos sobre poliomielite e desenvolvimento de tratamento sérico para meningite
1914	Paul Ehrlich	Frankfurt University, Germany	Hematologia, imunologia e quimioterapia antimicrobiana, descobriu a arsfenamina (Salvarsan), o primeiro tratamento medicinal eficaz para a sífilis, o conceito de uma bala de prata. Prêmio Nobel de 1908
1915	Lauder Brunton	St. Bartholomew's Hospital, London	Uso de nitrito de amila no tratamento da angina de peito
1920	Robert Jones	Military orthopaedic hospital at Liverpool	Radiografia em ortopedia, descreveu a fratura de Jones
1921	Jules Bordet	Université Libre de Bruxelles	Development of serological tests for syphilis, isolated Bordetella pertussis in pure culture in 1906 and posited it as the cause of whooping cough. Nobel Prize 1921
1922	F G Hopkins	University of Cambridge	Discovery of growth-stimulating vitamins, the amino acid tryptophan and the discovery and characterization of glutathione. Nobel Prize 1929
1923	John James Rickard Macleod	Universidade de Toronto	Isolation of insulin, Nobel Prize 1923
1924	Harvey Cushing	Harvard Medical School	Cushing's disease
1925	Rudolf Magnus	University Medical Center Utrecht	Diuretic effect of the excretions of the pituitary gland, the reflexes involved in mammal posture, studied the effects of narcotics and poison gasses on the lungs
1926	Henry Hallett Dale	National Institute for Medical Research	Study of acetylcholine as agent in the chemical transmission of nerve impulses. Nobel Prize 1936
1927	Frederick Banting	University of Toronto	Treated dogs so that they no longer produced trypsin, insulin could then be extracted and used to treat diabetes. Nobel Prize 1923
1928	Constantin Levaditi	Romanian University of Medicine and Pharmacy	Discovered in the presence of the polio virus in tissues other than nervous and this was the basis for the development of vaccine (by Jonas Salk and Albert Sabin)
1929	Leonard Rogers	Hospital for Tropical Diseases	Effects of hæmostatic and other drugs on the intravascular coagulability of the blood and treatment of cholera with hypertonic saline, worked on Entamoeba histolytica, which he correctly associated with both dysentery and hepatic abscess
1930	George R Minot	Harvard University	Discovered an effective treatment for pernicious anemia. Nobel Prize 1934
	William P. Murphy	Brigham Hospital, Boston	Shared the Nobel Prize in Physiology or Medicine in 1934 with George Richards Minot and George Hoyt Whipple combined work in devising and treating macrocytic anemia (specifically, pernicious anemia). liver had been tried on people with pernicious anemia and later were able to isolate vitamin B12
1931	Marie Curie	École Normale Supérieure	First woman to win a Nobel Prize with her husband, coined the word "radioactivity," and isolated radium chloride and pure radium. Nobel Prizes 1903 and 1911
1932	Edward Mellanby	Professor of Pharmacology at the University of Sheffield, Fullerian Professor of Physiology University of Cambridge	Cause of rickets is lack of vitamin, secretary of the Medical Research Council from 1933 to 1949
1933	Gladys Dick	University of Chicago, Evanston Hospital, John R. McCormick Institute for Infectious Diseases, St. Luke's Hospital	Isolated hemolytic streptococcus, co-developed a vaccine for scarlet fever, and introduced the Dick Test
	George Frederick Dick	University of Chicago, Evanston Hospital, John R. McCormick Institute for Infectious Diseases, St. Luke's Hospital	Isolated hemolytic streptococcus, co-developed a vaccine for scarlet fever, and introduced the Dick Test
1935	Edward Albert Sharpey Schafer	Escola de Medicina da Universidade de Edimburgo	Founder of endocrinology, coined the word "insulin" after theorising that a single substance from the pancreas was responsible for diabetes mellitus. Schafer's method of artificial respiration, introduced the use of suprarenal extract (containing adrenaline as well as other active substances)
1936	Julius Wagner-Jauregg	Clinic for Psychiatry and Nervous Diseases in Vienna	Introduced malaria inoculation in the treatment of dementia paralytica (neurosyphilis) and research on goiter, cretinism, and iodine. Nobel Prize 1927
1937	Carl Hamilton Browning	University of Glasgow	Worked in Germany with Paul Ehrlich, discovered the therapeutic qualities of acridine dyes
1938	James Collip	McGill University in Montreal	Working with the Toronto group that isolated insulin he prepared a pancreatic extract pure enough to be used in clinical trials, pioneering work with parathyroid hormone. Nobel Prize 1923
1938	Karl Landsteiner	Universidade de Viena Rockefeller Institute for Medical Research	Discovered three human blood groups (O, A, and B), the Rhesus factor, and isolated the polio virus. Nobel Prize 1930
1939	Gerhard Johannes Paul Domagk	Bayer laboratories at Wuppertal	Discoverer of sulfonamidochrysoidine (Prontosil) effective against streptococci, eventually led to the development of the antituberculosis drugs thiosemicarbazone and isoniazid. Nobel Prize 1939, lectured in 1954 (forced until then to decline Nobel Prize)
1940	Charles Dodds	Courtauld Institute of Biochemistry	Pentose phosphate pathway which generates NADPH, the discovery of stilboestrol, a synthetic and powerfully active non-steroid analogue of the naturally occurring oestrogenic hormone
1944	Otto Loewi	New York University College of Medicine	Showed Acetylcholine to be released by electrical stimulation of the vagus nerve and augmentation of adrenaline release by cocaine, a connection between digitalis and the action of calcium. Invented the mydriatic test in which an experimental form of diabetes in dogs led a change in the response of the eye to adrenaline. Nobel Prize 1936
1945	Alexander Fleming	St Mary's Hospital, London	Discovered the enzyme lysozyme in 1923 and the antibiotic substance benzylpenicillin (penicillin G) from the mould Penicillium notatum in 1928. Nobel Prize 1945 with Florey
1945	Howard Florey	University of Oxford	Carried out the first clinical trials of penicillin in 1941. Nobel Prize 1945 shared with Fleming
1946	Albert Szent-Györgyi	National Institutes of Health, Bethesda, Maryland	Discovering vitamin C and the components and reactions of the citric acid cycle, identifying fumaric acid and other steps in what became known as the Krebs cycle. Nobel Prize 1937
1947	Neil Hamilton Fairley	London School of Hygiene and Tropical Medicine	Saved thousands of Allied lives from malaria and other diseases during WW II, researched quinine, sulphonamides, atebrin, plasmoquine, and paludrine
1948	Edwin Bennett Astwood	New England Medical Center, Boston	Hormonal control of the mammary gland, the initial rise in uterine weight in response to estrogen could be suppressed by progesterone and the basic mechanisms of thyroid physiology and assessment of relative potency of antithyroid drugs in man, established rational therapeutic regimens for most thyroid diseases, identification of a third pituitary gonadotropin, which he named luteotrophin
1949	Daniel Bovet	University of Rome La Sapienza.	Antihistamines discovered succinylcholine to be a depolarizing muscle relaxant. He also synthesized gallamine, the first completely artificial curariform drug to be clinically useful, work on synthetic analogs of bioactive amines and antihistamines. Nobel Prize 1957
1950	Rudolph Peters	Institute of Animal Physiology, Babraham	British Anti-Lewisite (BAL) and treatment of post-arsphenamine jaundice researched pyruvate metabolism, focussing particularly on the toxicity of fluoroacetate
1951	Tadeus Reichstein	Pharmaceutical Institute of the University of Basel	Synthesized vitamin C (ascorbic acid) by what is now called the Reichstein process, isolated aldosterone, a hormone of the adrenal cortex. Nobel Prize 1950 Jointly with Kendall
	Edward Calvin Kendall	Universidade de Princeton	Isolation of thyroxine, the active principle of the thyroid gland, the crystallization of glutathione, the hormones of the cortex of the adrenal glands and the anti-inflammatory effect of cortisone. Nobel Prize 1950 (shared)
1954	Russell Brock	Guy's Hospital and the Royal Brompton Hospital	Cardiac surgeon, operated 0n Fallot’s Tetralogy patients with pulmonary stenosis and mitral stenosis resulting from rheumatic fever, introduced new developments, notably hypothermia and the heart-lung machine
1956	William D.M. Paton	University of Oxford	Interest in hyperbaric physiology, cholinergic transmission in particular decamethonium and hexamethonium, histamine release by licheniform and other basic substances, mechanism of action of gaseous anaesthetic agents, pharmacology of cannabis, the rate theory of drug action
	Eleanor Zaimis	The Royal Free Hospital, London	muscle relaxants and ganglionic blockers, the structure-activity relationships of methonium compounds
1958	Charles Huggins	University of Chicago	Discovered in 1941 that hormones could be used to control the spread of some cancers, specializing in prostate cancer, castration or estrogen administration led to glandular atrophy, androgen ablation of metastases, development of biomarker based on serum phosphatase. Nobel Prize 1966
1960	John F Enders	Children's Hospital Boston	In vitro culture of poliovirus, isolated measles virus and began development of measles vaccine and conducted trials on 1,500 mentally retarded children in New York City and 4,000 children in Nigeria. Nobel Prize 1954
1962	Alan S Parkes	University College, London	Reproductive biology, research in low-temperature biology leading to the discovery that glycerol protected spermatozoa against damage during freezing and storage at very low temperatures
1964	Willem J Kolff	University of Utah	Pioneer of hemodialysis for kidney failure and the development of artificial organs, in particular the artificial heart
1966	Gregory Pincus	Worcester Foundation for Experimental Biology in Shrewsbury, Massachusetts	Confirmed earlier research that progesterone would act as an inhibitor to ovulation, co-inventor the combined oral contraceptive pill, in vitro fertilization in rabbits
1968	Robert Gwyn Macfarlane	Oxford University	Deciphered the enzymic cascade of blood coagulation and the treatment of haemophilia, studied the venom of many different snakes and isolated the poison of the Russell's Viper
1970	Georges Mathé	Hôpital Paul-Brousse	Performed the first bone marrow graft and first successful kidney grafts between unrelated donors, the development of several important immunosuppressant molecules such as acriflavine, bestatine, ellipticine, oxaliplatin, triptoreline and vinorelbine
1972	George Hitchings	Wellcome Research Laboratories, Tuckahoe, New York	Work included 2,6-diaminopurine (a compound to treat leukemia) and p-chlorophenoxy-2,4-diaminopyrimidine (a folic acid antagonist), new drug therapies for malaria (pyrimethamine), leukemia (6-mercaptopurine and thioguanine), gout (allopurinol), organ transplantation (azathioprine) and bacterial infections (co-trimoxazole (trimethoprim) pointed the way that led to major antiviral drugs for herpes infections (acyclovir) and AIDS (zidovudine). Nobel Prize 1988 shared with Black
1974	John Charnley	Wrightington Hospital, Lancashire	British orthopaedic surgeon pioneered hip replacement, development of the low friction arthroplasty concept, use of bone cement that acted as a grout rather than glue
1976	Norman E Shumway	Stanford University	Human heart transplant operation, pioneered the use of cyclosporine to prevent rejection
1978	Sune K Bergstrom	Karolinska Institutet, Stockholm	Succeeded in producing pure prostaglandins and determining the chemical structures of two important examples, PGE and PGF, showed that these are formed through the conversion of unsaturated fatty acids, used to trigger contractions during childbirth, induce abortions, or reduce the risk of gastric ulcer. Nobel Prize 1982 Shared with John Vane
1980	James Black	King's College Hospital Medical School, London	Developed propranolol, a beta-blocker that has a calming effect on the heart by blocking the receptor for adrenaline,[3] developed cimetidine that suppresses the formation of gastric acid and is used to fight ulcers. Nobel Prize 1988 shared with Hitchings
1988	Hans Walter Kosterlitz	Faculdade de Ciências da Vida e Medicina da Universidade de Aberdeen	Endorphins, used electrically stimulated strip of guinea pig intestine to assess opiate activity in pig brain homogenates[4]
1990	Roy Yorke Calne	Universidade de Cambridge	organ transplantation pioneer, improvement of immunosuppression techniques
1993	Virgil Craig Jordan	Georgetown University Medical Center	Discovered the breast cancer prevention properties of tamoxifen, the prevention of multiple diseases in women using his new discovery, selective estrogen receptor modulators (SERMs) raloxifene trial
1996	Pat P A Humphrey	Glaxo	Pharmacological profile of selective 5-HT 4 receptor agonists, TD-5108, tegaserod, adenosine A1 receptor agonists.migraine,[5] 5-HT3 receptor antagonists in the treatment of irritable bowel syndrome, triptans as the most important breakthrough in headache medicine – sumatriptan, naratriptan, alosetron, ondansetron, vapiprost and salmeterol
2004	Ravinder Nath Maini	Imperial College School of Medicine	Identified TNF alpha as a key cytokine in rheumatoid arthritis and discoverer of anti-TNF therapy as an effective treatment
	Marc Feldmann	Kennedy Institute of Rheumatology, University of Oxford	Discoverer of anti-TNF therapy as an effective treatment for rheumatoid arthritis and other autoimmune diseases, infliximab and etanercept, treatments for Crohn's disease, ulcerative colitis, ankylosing spondylitis, psoriasis and psoriatic arthritis
2007	Garret Adare FitzGerald	Universidade da Pensilvânia	Prostanoid research, pharmacological inhibition of COXs versus the microsomal PGE synthase– 1,[6] involved in the interdisciplinary PENTACON consortium, integration of basic and clinical research in yeast, mammalian cells, fish, mice and humans with the objective of predicting NSAID efficacy and cardiovascular hazard in patients
2017	Sally Davies	Chief Medical Officer for England	Disorders of the blood and bone, sickle cell disease

Referências

1. «The Cameron Prize Lectures». Lancet. 206 (5332). 979 páginas. 1925. doi:10.1016/S0140-6736(01)69072-X
2. Sandrone, S (2014). «David Ferrier (1843-1928)» (PDF). J Neurol. 261 (6): 1247–1248. PMID 23846770. doi:10.1007/s00415-013-7023-y
3. Hothersall, J (2011). «The design, synthesis and pharmacological characterization of novel beta(2)-adrenoceptor antagonists». Br J Pharmacol. 164 (2): 317–31. PMC 3174413. PMID 21323900. doi:10.1111/j.1476-5381.2011.01269.x
4. Hughes, J (1975). «Identification of two related pentapeptides from the brain with potent opiate agonist activity.». Nature. 258 (5536): 577–580. Bibcode:1975Natur.258..577H. PMID 1207728. doi:10.1038/258577a0
5. Humphrey, P (2007). «The discovery of a new drug class for the acute treatment of migraine». Headache. 47 Suppl 1: S10-19. PMID 17425704. doi:10.1111/j.1526-4610.2007.00672.x
6. FitzGerald, Garret (2001). «COX-2 inhibitors and the cardiovascular system». Clin Exp Rheumatol. 19 (6 Suppl 25): S31-6. PMID 11695249