DMPK基因

DMPK基因
已知的结构
PDB	直系同源搜索: PDBe RCSB
PDBID列表
	1WT6、2VD5
识别号
别名	DMPK；, DM, DM1, DM1PK, DMK, MDPK, MT-PK, Dm15, dystrophia myotonica protein kinase, DM1 protein kinase
外部ID	OMIM：605377 MGI：94906 HomoloGene：3247 GeneCards：DMPK
相关疾病
	强直性肌肉失养症
基因位置（人类）
染色体	19号染色体
终止	45,782,552 bp
基因位置（小鼠）
染色体	小鼠7号染色体
终止	18,827,746 bp
RNA表达模式
	; ; ; ;
	查阅更多表达数据
基因本体
分子功能	• 蛋白质丝氨酸/苏氨酸激酶活性; • ATP结合; • myosin phosphatase regulator activity; • 蛋白激酶活性; • 血浆蛋白结合; • 激酶活性; • 金属离子结合; • 核苷酸结合; • 转移酶活性; • heat shock protein binding;
细胞组分	• integral component of membrane; • mitochondrial outer membrane; • 细胞核; • 肌浆网; • sarcoplasmic reticulum membrane; • 细胞质基质; • 膜; • 内质网; • mitochondrial membranes; • 细胞膜; • 细胞质; • nuclear outer membrane; • endoplasmic reticulum membrane; • 线粒体; • integral component of mitochondrial outer membrane; • 核膜;
生物学过程	• regulation of myotube differentiation; • muscle cell apoptotic process; • protein phosphorylation; • peptidyl-serine phosphorylation; • regulation of cardiac conduction; • regulation of sodium ion transport; • regulation of skeletal muscle contraction by calcium ion signaling; • nuclear envelope organization; • regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction; • regulation of synapse structural plasticity; • 磷酸化; • cellular calcium ion homeostasis; • regulation of heart contraction; • regulation of phosphoprotein phosphatase activity; • intracellular signal transduction;
	Sources:Amigo / QuickGO
直系同源
	1760
	13400
	ENSG00000104936
	ENSMUSG00000030409
	Q09013
	P54265
NM_001081560; NM_001081562; NM_001081563; NM_001288764; NM_001288765;
	NM_001288766; NM_004409
	NM_001190490; NM_001190491; NM_032418; NM_001374651; NM_001379257
NP_001075029; NP_001075031; NP_001075032; NP_001275693; NP_001275694;
	NP_001275695; NP_004400; NP_001275693.1; NP_001275694.1; NP_001275695.1
	NP_001177419; NP_001177420; NP_115794; NP_001361580; NP_001366186
	维基数据
查看/编辑人类	查看/编辑小鼠