Acrodermatitis enteropathica
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Acrodermatitis enteropathica is an autosomal recessive metabolic disorder affecting the uptake of zinc through the inner lining of the bowel, the mucous membrane. It is characterized by inflammation of the skin (dermatitis) around bodily openings (periorificial) and the tips of fingers and toes (acral), hair loss (alopecia), and diarrhea. It can also be related to deficiency of zinc due to other, i.e. congenital causes.[3][4]
Quick Facts Other names, Specialty ...
Acrodermatitis enteropathica | |
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Other names | Acrodermatitis enteropathica, zinc deficiency type[1] |
Acrodermatitis enteropathica inheritance | |
Specialty | Endocrinology |
Symptoms | Dry skin, Emotional lability, Blistering of skin[2] |
Causes | Mutation of the SLC39A4 gene[3] |
Diagnostic method | Skin biopsy, Plasma zinc level[3] |
Treatment | Dietary zinc supplementation[1] |
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Other names for acrodermatitis enteropathica include Brandt syndrome and Danbolt–Cross syndrome.[5]