Canavan disease
Neurodegenerative disorder / From Wikipedia, the free encyclopedia
Dear Wikiwand AI, let's keep it short by simply answering these key questions:
Can you list the top facts and stats about Canavan disease?
Summarize this article for a 10 year old
SHOW ALL QUESTIONS
Canavan disease, or Canavan–Van Bogaert–Bertrand disease, is a rare and fatal autosomal recessive[1] degenerative disease that causes progressive damage to nerve cells and loss of white matter in the brain.[2] It is one of the most common degenerative cerebral diseases of infancy.[3] It is caused by a deficiency of the enzyme aminoacylase 2,[4] and is one of a group of genetic diseases referred to as leukodystrophies. It is characterized by degeneration of myelin in the phospholipid layer insulating the axon of a neuron and is associated with a gene located on human chromosome 17.
Quick Facts Other names, Specialty ...
Canavan disease | |
---|---|
Other names | Canavan–van Bogaert–Bertrand disease |
Specialty | Endocrinology, neurology |
Close