1-Fluoro-2,4-dinitrobenzene
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1-Fluoro-2,4-dinitrobenzene (commonly called Sanger's reagent, dinitrofluorobenzene, DNFB or FDNB) is a chemical that reacts with the N-terminal amino acid of polypeptides. This can be helpful for sequencing proteins.
Quick Facts Names, Identifiers ...
Names | |
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Preferred IUPAC name
1-Fluoro-2,4-dinitrobenzene | |
Other names
Dinitrofluorobenzene Sanger's reagent | |
Identifiers | |
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3D model (JSmol) |
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Abbreviations | DNFB, FDNB |
ChEBI | |
ChEMBL | |
ChemSpider |
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ECHA InfoCard | 100.000.668 |
PubChem CID |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C6H3FN2O4 | |
Molar mass | 186.098 g·mol−1 |
Appearance | yellow crystals[1] |
Density | 1.4718 g·cm−3 (54 °C)[2] |
Melting point | 25.8 °C (78.4 °F; 298.9 K)[2] |
Boiling point | 296 °C (565 °F; 569 K)[2] |
Hazards | |
GHS labelling: | |
H301, H311, H331, H340, H350 | |
P260, P280, P282, P315 | |
Lethal dose or concentration (LD, LC): | |
LD50 (median dose) |
50 mg/kg-1 |
LDLo (lowest published) |
100 mg/kg-1 |
Safety data sheet (SDS) | [1] |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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