8-Hydroxyamoxapine
Chemical compound / From Wikipedia, the free encyclopedia
8-Hydroxyamoxapine is an active metabolite of the antidepressant drug amoxapine (Asendin). It contributes to amoxapine's pharmacology.[1][2] It is a serotonin-norepinephrine reuptake inhibitor (SNRI) with similar norepinephrine, but more serotonin, reuptake inhibition as its parent compound. It plays a part in balancing amoxapine's ratio of serotonin to norepinephrine transporter blockage.[3]
Quick Facts Pharmacokinetic data, Elimination half-life ...
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Elimination half-life | 30 hours |
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Formula | C17H16ClN3O2 |
Molar mass | 329.78 g·mol−1 |
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