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Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia
Disintegrin and metalloproteinase domain-containing protein 18 is an enzyme that in humans is encoded by the ADAM18 gene.[5][6]
ADAM18 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | ADAM18, ADAM27, tMDCIII, ADAM metallopeptidase domain 18 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | MGI: 105986; HomoloGene: 74941; GeneCards: ADAM18; OMA:ADAM18 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a sperm surface protein.[6]
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