Armodafinil
Eugeroic medication / From Wikipedia, the free encyclopedia
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Armodafinil (trade name Nuvigil) is the enantiopure compound of the eugeroic modafinil (Provigil).[3] It consists of only the (R)-(−)-enantiomer of the racemic modafinil. Armodafinil is produced by the pharmaceutical company Cephalon Inc.[4] and was approved by the U.S. Food and Drug Administration (FDA) in June 2007.[5][6] In 2016, the FDA granted Mylan rights for the first generic version of Cephalon's Nuvigil to be marketed in the U.S.[7]
Quick Facts Clinical data, Trade names ...
Clinical data | |
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Trade names | Nuvigil, others |
AHFS/Drugs.com | Monograph |
MedlinePlus | a602016 |
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Dependence liability | Low |
Routes of administration | Oral (tablets) |
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Metabolism | Liver, including CYP3A4 and other pathways |
Elimination half-life | 15 hours |
Excretion | Urine (as metabolites) |
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ECHA InfoCard | 100.207.833 |
Chemical and physical data | |
Formula | C15H15NO2S |
Molar mass | 273.35 g·mol−1 |
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Because armodafinil has a longer half-life than modafinil does, it may be more effective at improving wakefulness in patients with excessive daytime sleepiness.[8]