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BHLHE41

Protein-coding gene in the species Homo sapiens / From Wikipedia, the free encyclopedia

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"Basic helix-loop-helix family, member e41", or BHLHE41, is a gene that encodes a basic helix-loop-helix transcription factor repressor protein in various tissues of both humans and mice.[5][6][7][8] It is also known as DEC2, hDEC2, and SHARP1, and was previously known as "basic helix-loop-helix domain containing, class B, 3", or BHLHB3.[9] BHLHE41 is known for its role in the circadian molecular mechanisms that influence sleep quantity as well as its role in immune function and the maturation of T helper type 2 cell lineages associated with humoral immunity.[10][11]

Quick facts: BHLHE41, Identifiers, Aliases, External IDs, ...
BHLHE41
Identifiers
AliasesBHLHE41, DEC2, SHARP1, BHLHe41, HDEC2, SHARP-1, BHLHB3, Basic Helix-Loop-Helix Family Member E41, Basic Helix-Loop-Helix Family, Member E41, Class E Basic Helix-Loop-Helix Protein 41, Class B Basic Helix-Loop-Helix Protein 3, Basic Helix-Loop-Helix Domain Containing, Class B, 3, Differentially Expressed In Chondrocytes 2, Differentially Expressed In Chondrocytes Protein 2, Enhancer-Of-Split And Hairy-Related Protein 1, FNSS1
External IDsOMIM: 606200 MGI: 1930704 HomoloGene: 137401 GeneCards: BHLHE41
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_030762

NM_001271768
NM_024469

RefSeq (protein)

NP_110389

NP_001258697
NP_077789

Location (UCSC)Chr 12: 26.12 – 26.13 MbChr 6: 145.8 – 145.81 Mb
PubMed search[3][4]
Wikidata
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