Carmustine
Chemical compound / From Wikipedia, the free encyclopedia
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Carmustine, sold under the brand name BiCNU among others, is a medication used mainly for chemotherapy. It is a nitrogen mustard β-chloro-nitrosourea compound used as an alkylating agent.[7]
Quick Facts Names, Identifiers ...
Names | |
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IUPAC name
1,3-Bis(2-chloroethyl)-1-nitrosourea[1] | |
Other names
N,N'-Bis(2-chloroethyl)-N-nitrosourea, bis-chloroethylnitrosourea, BCNU | |
Identifiers | |
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3D model (JSmol) |
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ChEBI | |
ChEMBL | |
ChemSpider |
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DrugBank |
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ECHA InfoCard | 100.005.309 |
EC Number |
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KEGG |
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MeSH | Carmustine |
PubChem CID |
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RTECS number |
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UNII | |
UN number | 2811 |
CompTox Dashboard (EPA) |
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Properties | |
C5H9Cl2N3O2 | |
Molar mass | 214.05 g·mol−1 |
Appearance | Orange crystals |
Odor | Odourless |
Melting point | 30 °C (86 °F; 303 K) |
log P | 1.375 |
Acidity (pKa) | 10.194 |
Basicity (pKb) | 3.803 |
Pharmacology | |
L01AD01 (WHO) | |
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License data | |
Legal status | |
Hazards | |
GHS labelling: | |
Danger | |
H300, H350, H360 | |
P301+P310, P308+P313 | |
Lethal dose or concentration (LD, LC): | |
LD50 (median dose) |
20 mg kg−1 (oral, rat) |
Related compounds | |
Related ureas |
Dimethylurea |
Related compounds |
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Quick Facts Clinical data, Trade names ...
Clinical data | |
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Trade names | BiCNU, Gliadel |
AHFS/Drugs.com | Monograph |
MedlinePlus | a682060 |
License data |
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Drug class | Antineoplastic agents |
Legal status | |
Legal status | |
Identifiers | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.005.309 |
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