Clb 5,6 (Cdk1)
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Clb5 and Clb6 are B-type, S-phase cyclins in yeast that assist in cell cycle regulation.[1] Clb5 and Clb6 bind and activate Cdk1, and high levels of these cyclins are required for entering S-phase.[2] S-phase cyclin binding to Cdk1 directly stimulates DNA replication as well as progression to the next phase of the cell cycle.[3]