Gender dysphoria (GD) is the distress a person experiences due to a mismatch between their gender identitytheir personal sense of their own genderand their sex assigned at birth.[5][6] The diagnostic label gender identity disorder (GID) was used until 2013 with the release of the diagnostic manual DSM-5. The condition was renamed to remove the stigma associated with the term disorder.[7]

Quick facts: Gender dysphoria, Other names, Specialty, Sym...
Gender dysphoria
Other namesGender identity disorder
SpecialtyPsychiatry, psychology 
SymptomsDistress related to one's assigned gender, sex, and/or sex characteristics[1][2][3]
ComplicationsEating disorders, suicide, depression, anxiety, social isolation[4]
Differential diagnosisVariance in gender identity or expression that is not distressing[1][3]
TreatmentTransitioning, psychotherapy[2][3]
MedicationHormones (e.g., androgens, antiandrogens, estrogens)

People with gender dysphoria commonly identify as transgender.[8] Gender nonconformity is not the same thing as gender dysphoria[9] and does not always lead to dysphoria or distress.[10] According to the American Psychiatric Association, not all transgender people experience dysphoria;[9] the critical element of gender dysphoria is "clinically significant distress".[1]

The causes of gender incongruence are unknown but a gender identity likely reflects genetic, biological, environmental, and cultural factors.[11][12][13] Treatment for gender dysphoria may include supporting the individual's gender expression or their desire for hormone therapy or surgery.[2][3] Treatment may also include counseling or psychotherapy.[3]

Some researchers and transgender people support declassification of the condition because they say the diagnosis pathologizes gender variance and reinforces the binary model of gender.[14] Without the classification of gender dysphoria as a medical disorder, HRT and gender affirming surgery may be viewed as cosmetic treatments by health insurance, as opposed to medically necessary treatment, and may not be covered.[15]