Manolis Kellis
Greek-born computational biologist / From Wikipedia, the free encyclopedia
Manolis Kellis (Greek: Μανώλης Καμβυσέλλης; born 1977) is a professor of Computer Science and Computational Biology at the Massachusetts Institute of Technology (MIT) and a member of the Broad Institute of MIT and Harvard.[3] He is the head of the Computational Biology Group at MIT[4] and is a Principal Investigator in the Computer Science and Artificial Intelligence Lab (CSAIL) at MIT.[5]
Manolis Kellis | |
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Born | (1977-03-13) March 13, 1977 (age 47) |
Alma mater | Massachusetts Institute of Technology (PhD) |
Known for | ENCODE |
Awards | |
Scientific career | |
Fields | |
Thesis | Computational Comparative Genomics: Genes, Regulation, Evolution. (2003) |
Doctoral advisor | |
Website | compbio |
Kellis is known for his contributions to genomics, human genetics, epigenomics, gene regulation, genome evolution, disease mechanism, and single-cell genomics. He co-led the NIH Roadmap Epigenomics Project[6] effort to create a comprehensive map of the human epigenome,[7][8][9] the comparative analysis of 29 mammals to create a comprehensive map of conserved elements in the human genome,[10][11] the ENCODE, GENCODE, and modENCODE projects to characterize the genes, non-coding elements, and circuits of the human genome and model organisms.[12][13][14] A major focus of his work is understanding the effects of genetic variations on human disease,[15] with contributions to obesity,[16][17][18] diabetes,[19] Alzheimer's disease,[20][21][22] schizophrenia,[23] and cancer.[24]