Mouse brain
Body part used for neuroscience research / From Wikipedia, the free encyclopedia
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The mouse brain refers to the brain of Mus musculus. Various brain atlases exist.
The article's lead section may need to be rewritten. (April 2019) |
For reasons of reproducibility, genetically characterized, stable strains like C57BL/6 were chosen to produce high-resolution images and databases.[1] Well known online resources include:
- Allen Brain Atlas[2]
- Mouse Brain Library[3]
- High resolution mouse brain atlas
- BrainMaps
Despite superficial differences, especially in size and weight, the mouse brain and its function can serve as a powerful animal model for study of human brain diseases or mental disorders (see e.g. Reeler, Chakragati mouse). This is because the genes responsible for building and operating both mouse and human brain are 90% identical.[4] Transgenic mouse lines also allow neuroscientists to specifically target the labeling of certain cell types to probe the neural basis of fundamental processes.[5][6]