NFE2L3
Protein-coding gene in the species Homo sapiens / From Wikipedia, the free encyclopedia
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Nuclear factor (erythroid 2)-like factor 3, also known as NFE2L3 or 'NRF3', is a transcription factor that in humans is encoded by the Nfe2l3 gene.[5][6]
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Nrf3 is a basic leucine zipper (bZIP) transcription factor belonging to the Cap ‘n’ Collar (CNC) family of proteins.[7] In 1989, the first CNC transcription factor NFE2L2 was identified. Subsequently, several related proteins were identified, including NFE2L1 and NFE2L3, in different organisms such as humans, mice, and zebrafish.[8] These proteins are specifically encoded in the humans by Nfe2l1 and Nfe2l3 genes respectively.[9][10]