Neuropathic arthropathy
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"Charcot joint disease" redirects here. For other uses, see Charcot disease.
"Charcot foot" redirects here. For the hereditary condition that also causes foot deformity, see Charcot–Marie–Tooth disease.
Neuropathic arthropathy (or neuropathic osteoarthropathy), also known as Charcot joint (often Charcot foot) after the first to describe it, Jean-Martin Charcot, refers to progressive degeneration of a weight-bearing joint, a process marked by bony destruction, bone resorption, and eventual deformity due to loss of sensation. Onset is usually insidious.
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If this pathological process continues unchecked, it can result in joint deformity, ulceration and/or superinfection, loss of function, and in the worst-case scenario, amputation or death. Early identification of joint changes is the best way to limit morbidity.