Povidone-iodine
Antiseptic solution / From Wikipedia, the free encyclopedia
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Povidone-iodine (PVP-I), also known as iodopovidone, is an antiseptic used for skin disinfection before and after surgery.[1][2] It may be used both to disinfect the hands of healthcare providers and the skin of the person they are caring for.[2] It may also be used for minor wounds.[2] It may be applied to the skin as a liquid or a powder.[2]
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Trade names | Betadine, Wokadine, Pyodine, others |
Other names | polyvidone iodine, iodopovidone |
AHFS/Drugs.com | Consumer Drug Information |
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Routes of administration | Topical |
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ECHA InfoCard | 100.110.412 |
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Formula | (C6H9NO)n·xI |
Molar mass | variable |
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Side effects include skin irritation and sometimes swelling.[1] If used on large wounds, kidney problems, high blood sodium, and metabolic acidosis may occur.[1] It is not recommended in women who are less than 32 weeks pregnant.[2] Frequent use is not recommended in people with thyroid problems or who are taking lithium.[2]
Povidone-iodine is a chemical complex of povidone, hydrogen iodide, and elemental iodine.[3] The recommended strength solution contains 10% Povidone, with total iodine species equaling 10,000 ppm or 1% total titratable iodine.[3] It works by releasing iodine which results in the death of a range of microorganisms.[1]
Povidone-iodine came into commercial use in 1955.[4] It is on the World Health Organization's List of Essential Medicines.[5] Povidone-iodine is available over the counter.[6] It is sold under a number of brand names including Betadine.[2]