Succimer
Medication used to treat lead, mercury, and arsenic poisoning / From Wikipedia, the free encyclopedia
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Succimer, sold under the brand name Chemet among others, is a medication used to treat lead, mercury, and arsenic poisoning.[4] When radiolabeled with technetium-99m, it is used in many types of diagnostic testing.[5] A full course of Succimer lasts for 19 days of oral administration.[4] A second course should be given when more than two weeks pass after the first course.[4]
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Pronunciation | /ˈsʌksɪmər/ |
Trade names | Chemet, others |
Other names | Dimercaptosuccinic acid DMSA (2R,3S)-2,3-Dimercaptosuccinic acid meso-2,3-Dimercaptosuccinic acid APRD01236 |
AHFS/Drugs.com | Monograph |
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ECHA InfoCard | 100.005.597 |
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Formula | C4H6O4S2 |
Molar mass | 182.21 g·mol−1 |
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Melting point | 125 °C (257 °F) |
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Common side effects include vomiting, diarrhea, rash, and low blood neutrophil levels.[4] Liver problems and allergic reactions may also occur with use.[4] Whether use during pregnancy is safe for the baby is unclear.[6] Dimercaptosuccinic acid is in the chelating agent family of medications.[4] It works by binding with lead and a number of other heavy metals, allowing them to leave the body in the urine.[4]
Succimer has been used medically since the 1950s.[7][8] It is on the World Health Organization's List of Essential Medicines.[9] In the United States, no generic version was available as of 2015.[10]