Tetrahydrocannabiphorol
Cannabinoid agonist compound / From Wikipedia, the free encyclopedia
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Tetrahydrocannabiphorol (THCP) is a potent phytocannabinoid, a CB1 and CB2 agonist which was known as a synthetic homologue of THC,[1] but for the first time in 2019 was isolated as a natural product in trace amounts from Cannabis sativa.[2][3] It is structurally similar to Δ9-THC, the main active component of cannabis, but with the pentyl side chain extended to heptyl. Since it has a longer side chain, its cannabinoid effects are "far higher than Δ9-THC itself." Tetrahydrocannabiphorol has a reported binding affinity of 1.2 nM at CB1, approximately 33 times that of Δ9-THC (40 nM at CB1).[4]
Not to be confused with Tetrakis(hydroxymethyl)phosphonium chloride (THPC).
See also: Cannabidiphorol (CBDP)
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Quick Facts Clinical data, Other names ...
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Other names | (-)-Trans-Δ9-tetrahydrocannabiphorol Δ9-THCP (C7)-Δ9-THC THC-Heptyl |
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Formula | C23H34O2 |
Molar mass | 342.523 g·mol−1 |
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THCP was studied by Roger Adams as early as 1942.[5]