Tiopronin
Chemical compound / From Wikipedia, the free encyclopedia
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Tiopronin, sold under the brand name Thiola, is a medication used to control the rate of cystine precipitation and excretion in the disease cystinuria.[3][4]
Quick Facts Names, Identifiers ...
Names | |
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IUPAC name
N-(2-Sulfanylpropanoyl)glycine | |
Systematic IUPAC name
(2-Sulfanylpropanamido)acetic acid | |
Other names
2-mercaptopropionylglycine Acadione | |
Identifiers | |
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3D model (JSmol) |
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1859822 | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.016.163 |
EC Number |
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KEGG |
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MeSH | Tiopronin |
PubChem CID |
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RTECS number |
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UNII |
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CompTox Dashboard (EPA) |
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Properties | |
C5H9NO3S | |
Molar mass | 163.19 g·mol−1 |
Appearance | White, opaque crystals |
Melting point | 93 to 98 °C (199 to 208 °F; 366 to 371 K) |
log P | −0.674 |
Acidity (pKa) | 3.356 |
Basicity (pKb) | 10.641 |
Pharmacology | |
G04BX16 (WHO) QG04BX16 (WHO) | |
By mouth | |
Legal status | |
Hazards | |
GHS labelling: | |
Warning | |
H302 | |
Lethal dose or concentration (LD, LC): | |
LD50 (median dose) |
1,300 mg kg−1 (oral, rat) |
Related compounds | |
Related alkanoic acids |
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Related compounds |
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Quick Facts Clinical data, Trade names ...
Clinical data | |
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Trade names | Thiola |
License data | |
Identifiers | |
DrugBank | |
ChEBI | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.016.163 |
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It is available as a generic medication.[5][6]