1cP-MiPLA

1cP-MiPLA, also known as 1-cyclopropanoyl-MiPLA or 1-cyclopropanoyl-N-methyl-N-isopropyllysergamide, is a presumed psychedelic drug of the lysergamide family.^[1][2][3] It is the 1-cyclopropanoyl derivative of MiPLA (N-methyl-N-isopropyllysergamide) and is thought to be a prodrug of MiPLA.^[1][2][3] 1cP-MiPLA has been encountered as a novel designer drug online^[1] and in Japan.^[2][3]

1cP-MiPLA

Clinical data
Other names	1cP-MIPLA; 1-Cyclopropanoyl-MiPLA; 1-Cyclopropanoyl-N-methyl-N-isopropyllysergamide; 1-(Cyclopropanecarbonyl)-N,6-dimethyl-N-(propan-2-yl)-9,10-didehydroergoline-8β-carboxamide
Routes of administration	Oral[1][2][3]
Drug class	Serotonin receptor modulator; Serotonin 5-HT2A receptor agonist; Serotonergic psychedelic; Hallucinogen
ATC code	None
Identifiers
IUPAC name (6aR,9R)-4-(cyclopropanecarbonyl)-N,7-dimethyl-N-(propan-2-yl)-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
CAS Number	3028950-74-2
PubChem CID	170763684
ChemSpider	128938072
Chemical and physical data
Formula	C24H29N3O2
Molar mass	391.515 g·mol−1
3D model (JSmol)	Interactive image
SMILES CN1C[C@@H](C=C2[C@H]1Cc1cn(c3c1c2ccc3)C(=O)C1CC1)C(=O)N(C(C)C)C
InChI InChI=1S/C24H29N3O2/c1-14(2)26(4)23(28)17-10-19-18-6-5-7-20-22(18)16(11-21(19)25(3)12-17)13-27(20)24(29)15-8-9-15/h5-7,10,13-15,17,21H,8-9,11-12H2,1-4H3/t17-,21-/m1/s1 Key:DBIYDHUGEKMIHZ-DYESRHJHSA-N

Use and effects

See also: MiPLA § Use and effects

1cP-MiPLA has been sold in the form of blotter tabs containing doses of 200 μg per tab.^[1] Data on the effects of 1cP-MiPLA at different doses are not available.^[1]

Interactions

See also: Psychedelic drug § Interactions, and Trip killer § Serotonergic psychedelic antidotes

Pharmacology

1cP-MiPLA is assumed to act as a prodrug of MiPLA via deacylation.^[2][3] Relatedly, it is assumed to act as a serotonin receptor agonist, including of the serotonin 5-HT_2A receptor, and to be a serotonergic psychedelic.^[1]

Chemistry

Analogues

Analogues of 1cP-MiPLA include MiPLA, 1P-MiPLA, and 1cP-AL-LAD, among others.

History

1cP-MiPLA was first encountered as a novel designer drug online in 2020^[1] and in Japan by 2022.^[2][3]

Society and culture

Legal status

Russia

1cP-MiPLA is a schedule I controlled substance in Russia.^[1]

See also

• Substituted lysergamide
• Lizard Labs