2-MAPB

2-MAPB is a recreational designer drug with empathogenic effects. As with other related substituted benzofuran derivatives such as 6-APB and 5-MAPB, 2-MAPB is a monoamine releaser with some selectivity for serotonin release, generally similar in pharmacological profile to MDMA but with greater activity as a directly acting agonist of 5-HT₂ receptor subtypes and somewhat greater toxicity.^[1] 2-MAPB has been isolated from post-mortem toxicology screens in several drug-related fatal adverse reactions but generally only as a component of combinations of drugs, making it difficult to determine how much it contributed to the deaths.^[2][3] It is illegal in Japan.^[4]

2-MAPB

Identifiers
IUPAC name 1-(1-benzofuran-2-yl)-N-methylpropan-2-amine
CAS Number	806596-15-6 Y
PubChem CID	547092
ChemSpider	476194
UNII	W5G20WN7CL
CompTox Dashboard (EPA)	DTXSID901016908
Chemical and physical data
Formula	C12H15NO
Molar mass	189.258 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(CC1=CC2=CC=CC=C2O1)NC
InChI InChI=1S/C12H15NO/c1-9(13-2)7-11-8-10-5-3-4-6-12(10)14-11/h3-6,8-9,13H,7H2,1-2H3 Key:ANJIDHKQUCZNQY-UHFFFAOYSA-N

See also

• Benzofuranylpropylaminopentane
• Dimemebfe
• 5-Methylmethiopropamine
• Methamnetamine