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Substituted benzofuran
Class of chemical compounds From Wikipedia, the free encyclopedia
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The substituted benzofurans are a class of chemical compounds based on the heterocyclic and polycyclic compound benzofuran. Many medicines use the benzofuran core as a scaffold,[1][2][3] but most commonly the term is used to refer to the simpler compounds in this class which include numerous psychoactive drugs, including stimulants, psychedelics and empathogens. In general, these compounds have a benzofuran core to which a 2-aminoethyl group is attached (at any position), and combined with a range of other substituents.[4][5][6][7] Some psychoactive derivatives from this family have been sold under the name Benzofury.[8]
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List of substituted benzofurans
Summarize
Perspective
The derivatives may be produced by substitutions at six locations of the benzofuran molecule, as well as saturation of the 2,3- double bond.
The following table displays notable derivatives that have been reported:[9][10][11][12][13][14][15][16][17][18][19]
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Legislation
Substituted benzofurans saw widespread use as recreational drugs by being sold as research chemicals making them exempt from drug legislation. Many of the more common compounds were banned in the UK in June 2013 as temporary class drugs, while others have been made permanently illegal in various jurisdictions.[21][22][23]
See also
- 2-Aminoethoxydiphenyl borate (an unrelated compound also known as 2-APB)
- 2C-B-BUTTERFLY
- 5-IT
- AL-38022A
- IBF5MAP
- Jimscaline
- Oxa-noribogaine
- Substituted amphetamine
- Substituted benzothiophene
- Substituted cathinone
- Substituted methylenedioxyphenethylamine
- Substituted methoxyphenethylamine
- Substituted naphthylethylamine
- Substituted phenethylamine
- Substituted tryptamines
References
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