2C-T-25

2C-T-25, also known as 4-isobutylthio-2,5-dimethoxyphenethylamine, is a serotonin receptor modulator of the phenethylamine and 2C families.^[1][2][3][4] It shows affinity for serotonin receptors and other targets and acts as a potency partial agonist of the serotonin 5-HT_2A and 5-HT_2B receptors.^[4] The dose of 2C-T-25 in humans is unknown.^[5] Daniel Trachsel reported that 2C-T-25 was inactive at doses of up to 30 mg orally.^[1] The drug was first described in the scientific literature by Trachsel in 2003 and was subsequently described further by Trachsel and colleagues in 2013 and 2018.^[1][2][3][4]

2C-T-25

Clinical data
Other names	4-Isobutylthio-2,5-dimethoxyphenethylamine; 4-iBuS-2,5-DMPEA
Routes of administration	Oral[1]
Drug class	Serotonin receptor modulator; Serotonin 5-HT2A receptor agonist
ATC code	None
Identifiers
IUPAC name 2-[2,5-dimethoxy-4-(2-methylpropylsulfanyl)phenyl]ethanamine
PubChem CID	12063260
ChemSpider	67168652
Chemical and physical data
Formula	C14H23NO2S
Molar mass	269.40 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(C)CSC1=C(C=C(C(=C1)OC)CCN)OC
InChI InChI=1S/C14H23NO2S/c1-10(2)9-18-14-8-12(16-3)11(5-6-15)7-13(14)17-4/h7-8,10H,5-6,9,15H2,1-4H3 Key:OEPKQBQEDYEXMC-UHFFFAOYSA-N

See also

• 2C (psychedelics)