2C-T-35

2C-T-35 (2C-T-DFM) is a designer drug from the substituted phenethylamine family, which was first synthesised by Josh Hartsel and colleagues in 2024. It is a potent agonist at the serotonin receptor 5-HT_2A in vitro, with a binding affinity (K_i) of 6.3 nM. In animal studies, 2C-T-DFM was the most effective compound at producing a head-twitch response out of a series of related analogues, with an average of 33 head-twitches per 10 minutes compared to 21 for 2C-T-TFM.^[1] While it had previously been proposed as a theoretical compound, 2C-T-35 is not known to have been tested in humans.^[2]

2C-T-35

Identifiers
IUPAC name 2-[4-(difluoromethylsulfanyl)-2,5-dimethoxyphenyl]ethanamine
PubChem CID	169149411
Chemical and physical data
Formula	C11H15F2NO2S
Molar mass	263.30 g·mol−1
3D model (JSmol)	Interactive image
SMILES COC1=CC(=C(C=C1CCN)OC)SC(F)F
InChI InChI=1S/C11H15F2NO2S/c1-15-8-6-10(17-11(12)13)9(16-2)5-7(8)3-4-14/h5-6,11H,3-4,14H2,1-2H3 Key:IMXLEUNJGUBEMC-UHFFFAOYSA-N

See also

• 2C-T-21.5
• 2C-T-29