4,5-DHP-DMT

1-(2-Dimethylaminoethyl)dihydropyrano(3,2-e)indole (4,5-DHP-DMT) is a tricyclic tryptamine derivative which acts as a potent and reasonably selective partial agonist for the serotonin receptor 5-HT_2A, with a K_i of 17.0 nM, and moderate selectivity over related serotonin receptors. It has lower 5-HT₂ affinity and efficacy than the related compound AL-37350A, but higher lipophilicity.^[1][2]

4,5-DHP-DMT

Identifiers
IUPAC name 1-(2-Dimethylaminoethyl)-8,9-dihydropyrano[3,2-e]indole
CAS Number	135360-97-3 Y
PubChem CID	15011385
ChemSpider	19425248 Y
UNII	UW9YPK64EU
ChEMBL	ChEMBL412876
CompTox Dashboard (EPA)	DTXSID10566920
Chemical and physical data
Formula	C15H20N2O
Molar mass	244.338 g·mol−1
3D model (JSmol)	Interactive image
SMILES CN(C)CCc1c[nH]c3ccc2OCCCc2c13
InChI InChI=1S/C15H20N2O/c1-17(2)8-7-11-10-16-13-5-6-14-12(15(11)13)4-3-9-18-14/h5-6,10,16H,3-4,7-9H2,1-2H3 N Key:RMMYVKPVLLBYDW-UHFFFAOYSA-N N
NY (what is this?)  (verify)

See also

• 4,5-MDO-DMT
• 4,5-MDO-DiPT
• 5-MeO-DMT
• CP-132,484
• RU-28306
• Ramelteon