4-APBT

4-APBT, also known as 4-(2-aminopropyl)-1-benzothiophene, is a monoamine releasing agent (MRA) of the amphetamine and benzothiophene families.^[1][2] It acts specifically as a fairly well-balanced serotonin–norepinephrine–dopamine releasing agent (SNDRA), with EC₅₀Tooltip half-maximal effective concentration values of 21.2 nM for serotonin, 46.2 nM for norepinephrine, and 66.6 nM for dopamine in rat brain synaptosomes.^[2] 4-APBT was first described in the scientific literature by 2020.^[1][2]

4-APBT

Clinical data
Other names	4-(2-Aminopropyl)-1-benzothiophene
Drug class	Serotonin–norepinephrine–dopamine releasing agent
Identifiers
IUPAC name 1-(1-benzothiophen-4-yl)propan-2-amine
Chemical and physical data
Formula	C11H13NS
Molar mass	191.29 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(Cc1cccc2c1ccs2)N
InChI InChI=1S/C11H13NS/c1-8(12)7-9-3-2-4-11-10(9)5-6-13-11/h2-6,8H,7,12H2,1H3 Key:NKOJSEHZOSSUEN-UHFFFAOYSA-N

See also

• 5-APBT
• 6-APBT
• 7-APBT