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5-HT1F receptor

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

5-HT1F receptor
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5-hydroxytryptamine (serotonin) receptor 1F, also known as HTR1F is a 5-HT1 receptor protein and also denotes the human gene encoding it.[5][6][7][8][9]

Quick Facts HTR1F, Identifiers ...
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Agonists

  • 5-n-Butyryloxy-DMT:[10] >60-fold selectivity versus 5-HT1E receptor
  • BRL-54443 - mixed 5-HT1E/1F agonist
  • Eletriptan - mixed 5-HT1B/1D/1E/1F/2B/7 agonist
  • LY-334,370[11] - as well as related benzamides[12]
  • LY-344,864 (N-[(3R)-3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamide)
  • Naratriptan - mixed 5-HT1B/1D/1F agonist
  • Lasmiditan - selective 5-HT1F agonist, a first-in-class ditan molecule
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Antagonists

MLS000756415[13]

See also

References

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Further reading

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