5-HT5B receptor

5-HT_5B receptor is a 5-HT receptor protein and the gene which encodes it. The protein is found in rodents, but not in humans, because stop codons in the gene's coding sequence prevent the gene from expressing a functional protein.^[4] It is believed that the function of the 5-HT_5B receptor has been replaced in humans by some other subclass of 5-HT receptor.^[5] 5-HT_5B receptor is a G protein-coupled receptor.^[6] 5-HT_5B receptor mRNA is expressed primarily in the habenula, hippocampus and inferior olive of rat brains.^[7] Known agonists for 5-HT_5B include ergotamine and LSD. Known antagonists include methiothepin.

HTR5BP
Identifiers
Aliases	HTR5BP, 5-HT5B, GPR134, HTR5B, 5-hydroxytryptamine receptor 5B, pseudogene
External IDs	MGI: 96284; GeneCards: HTR5BP; OMA:HTR5BP - orthologs
Gene location (Mouse) Chr. Chromosome 1 (mouse)[1] Band 1 E2.3|1 52.98 cM Start 121,437,571 bp[1] End 121,456,194 bp[1]
Orthologs Species Human Mouse Entrez 645694 15564 Ensembl ENSG00000125631 ENSMUSG00000050534 UniProt n a P31387 RefSeq (mRNA) n/a NM_010483 RefSeq (protein) n/a NP_034613 Location (UCSC) n/a Chr 1: 121.44 – 121.46 Mb PubMed search [2] [3]
Wikidata
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