ACIN1

Apoptotic chromatin condensation inducer in the nucleus is a protein that in humans is encoded by the ACIN1 gene.^[5][6][7]

ACIN1
Identifiers
Aliases	ACIN1, ACINUS, ACN, fSAP152, apoptotic chromatin condensation inducer 1
External IDs	OMIM: 604562; MGI: 1891824; HomoloGene: 22853; GeneCards: ACIN1; OMA:ACIN1 - orthologs
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q11.2 Start 23,058,564 bp[1] End 23,095,614 bp[1]
Gene location (Mouse) Chr. Chromosome 14 (mouse)[2] Band 14|14 C2 Start 54,642,161 bp[2] End 54,686,931 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right uterine tube right lobe of thyroid gland sural nerve left lobe of thyroid gland right ovary left ovary body of uterus canal of the cervix right adrenal cortex anterior pituitary Top expressed in neural layer of retina tail of embryo ventricular zone genital tubercle yolk sac granulocyte Rostral migratory stream primary visual cortex superior frontal gyrus lip More reference expression data BioGPS More reference expression data
Gene ontology Molecular function ATPase activity protein binding enzyme binding nucleic acid binding RNA binding Cellular component nuclear speck plasma membrane exon-exon junction complex nucleoplasm nucleolus ASAP complex nucleus cytosol Biological process apoptotic chromosome condensation mRNA processing negative regulation of mRNA splicing, via spliceosome RNA splicing positive regulation of apoptotic process positive regulation of monocyte differentiation erythrocyte differentiation apoptotic process execution phase of apoptosis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 22985 56215 Ensembl ENSG00000100813 ENSMUSG00000022185 UniProt Q9UKV3 Q9JIX8 RefSeq (mRNA) NM_001164814 NM_001164815 NM_001164816 NM_001164817 NM_014977 NM_001386863 NM_001085472 NM_001085473 NM_001242605 NM_001242606 NM_019567 NM_023190 RefSeq (protein) NP_001158286 NP_001158287 NP_001158288 NP_001158289 NP_055792 NP_001078941 NP_001078942 NP_001229534 NP_001229535 NP_062513 NP_075679 NP_001361699 Location (UCSC) Chr 14: 23.06 – 23.1 Mb Chr 14: 54.64 – 54.69 Mb PubMed search [3] [4]
Wikidata
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