ACOT12

Acyl-coenzyme A thioesterase 12 or StAR-related lipid transfer protein 15 (STARD15) is an enzyme that in humans is encoded by the ACOT12 gene.^[5][6][7] The protein contains a StAR-related lipid transfer domain.

ACOT12
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3B7K, 4MOB, 4MOC
Identifiers
Aliases	ACOT12, CACH-1, Cach, STARD15, THEAL, acyl-CoA thioesterase 12
External IDs	OMIM: 614315; MGI: 1921406; HomoloGene: 12540; GeneCards: ACOT12; OMA:ACOT12 - orthologs
Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5q14.1 Start 81,329,996 bp[1] End 81,394,179 bp[1]
Gene location (Mouse) Chr. Chromosome 13 (mouse)[2] Band 13|13 C3 Start 91,889,631 bp[2] End 91,934,267 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of liver testicle buccal mucosa cell human kidney duodenum gonad Achilles tendon stromal cell of endometrium hypothalamus muscle tissue Top expressed in right kidney human kidney left lobe of liver proximal tubule jejunum intestinal villus duodenum seminiferous tubule epithelium of small intestine embryo More reference expression data BioGPS More reference expression data
Gene ontology Molecular function carboxylic ester hydrolase activity ATP binding hydrolase activity lipid binding acetyl-CoA hydrolase activity acyl-CoA hydrolase activity fatty-acyl-CoA binding palmitoyl-CoA hydrolase activity long-chain fatty acyl-CoA binding thiolester hydrolase activity Cellular component cytoplasm cytosol Biological process pyruvate metabolic process lipid metabolism acyl-CoA metabolic process acetyl-CoA metabolic process fatty acid metabolic process palmitic acid biosynthetic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 134526 74156 Ensembl ENSG00000172497 ENSMUSG00000021620 UniProt Q8WYK0 Q9DBK0 RefSeq (mRNA) NM_130767 NM_028790 RefSeq (protein) NP_570123 NP_083066 Location (UCSC) Chr 5: 81.33 – 81.39 Mb Chr 13: 91.89 – 91.93 Mb PubMed search [3] [4]
Wikidata
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