ACTR3B

Actin-related protein 3B also known as ARP3-beta is a protein that in humans is encoded by the ACTR3B gene.^[4] Pseudogenes of this gene are located on chromosomes 2, 4, 10, 16, 22 and Y. Alternative splicing results in multiple transcript variants and protein isoforms.^[4]

ACTR3B
Identifiers
Aliases	ACTR3B, ARP11, ARP3BETA, ARP3 actin-related protein 3 homolog B (yeast)
External IDs	MGI: 2661120; HomoloGene: 4180; GeneCards: ACTR3B; OMA:ACTR3B - orthologs
Gene location (Mouse) Chr. Chromosome 5 (mouse)[1] Band 5|5 B1 Start 25,964,995 bp[1] End 26,055,686 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) n/a Top expressed in hippocampus proper dorsal striatum olfactory tubercle dentate gyrus visual cortex dentate gyrus of hippocampal formation granule cell superior frontal gyrus primary visual cortex piriform cortex subdivision of hippocampus BioGPS More reference expression data
Gene ontology Molecular function ATP binding nucleotide binding actin binding molecular function actin filament binding Cellular component arp2/3 protein complex cell projection cytoplasm cytoskeleton extracellular exosome Biological process actin filament organization Arp2/3 complex-mediated actin nucleation biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 57180 242894 Ensembl ENSG00000133627 ENSMUSG00000056367 UniProt Q9P1U1 Q641P0 RefSeq (mRNA) NM_001040135 NM_020445 NM_001004365 NM_001310504 RefSeq (protein) NP_001035225 NP_065178 NP_001337869 NP_001337870 NP_001337871 NP_001337872 NP_001337873 NP_001337874 NP_001337875 NP_001004365 NP_001297433 Location (UCSC) n/a Chr 5: 25.96 – 26.06 Mb PubMed search [2] [3]
Wikidata
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Function

This gene encodes a member of the actin-related proteins (ARP), which form multiprotein complexes and share 35-55% amino acid identity with conventional actin. The protein encoded by this gene may have a regulatory role in the actin cytoskeleton and induce cell-shape change and motility.^[4]