ADAMTS15

A disintegrin and metalloproteinase with thrombospondin motifs 15 is a protein in humans encoded by the ADAMTS15 gene, a member of the ADAMTS family of multidomain extracellular protease enzymes.

ADAMTS15
Identifiers
Aliases	ADAMTS15, ADAM metallopeptidase with thrombospondin type 1 motif 15
External IDs	OMIM: 607509; MGI: 2449569; HomoloGene: 8610; GeneCards: ADAMTS15; OMA:ADAMTS15 - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q24.3 Start 130,448,645 bp[1] End 130,476,645 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 A4 Start 30,810,451 bp[2] End 30,833,748 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in decidua myocardium of left ventricle cardiac muscle tissue of right atrium parietal pleura right ventricle apex of heart lactiferous duct right auricle of heart left uterine tube tibial arteries Top expressed in aortic valve ascending aorta lumbar spinal ganglion internal carotid artery external carotid artery tunica media of zone of aorta left colon trigeminal ganglion gastric mucosa mucous cell of stomach More reference expression data BioGPS n/a
Gene ontology Molecular function zinc ion binding peptidase activity metalloendopeptidase activity heparin binding endopeptidase activity hydrolase activity metallopeptidase activity extracellular matrix binding metal ion binding Cellular component extracellular region cell surface extracellular space collagen-containing extracellular matrix Biological process proteolysis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 170689 235130 Ensembl ENSG00000166106 ENSMUSG00000033453 UniProt Q8TE58 P59384 RefSeq (mRNA) NM_139055 NM_001024139 NM_001329420 RefSeq (protein) NP_620686 NP_001019310 NP_001316349 Location (UCSC) Chr 11: 130.45 – 130.48 Mb Chr 9: 30.81 – 30.83 Mb PubMed search [3] [4]
Wikidata
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