ADAP2

Arf-GAP with dual PH domain-containing protein 2 is a protein that in humans is encoded by the ADAP2 gene.^[5]

ADAP2
Identifiers
Aliases	ADAP2, CENTA2, HSA272195, cent-b, ArfGAP with dual PH domains 2
External IDs	OMIM: 608635; MGI: 2663075; HomoloGene: 10179; GeneCards: ADAP2; OMA:ADAP2 - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q11.2 Start 30,906,344 bp[1] End 30,959,322 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11 B5|11 47.56 cM Start 80,154,105 bp[2] End 80,178,958 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in monocyte synovial membrane amniotic fluid granulocyte placenta spleen trabecular bone gingival epithelium blood synovial joint Top expressed in Rostral migratory stream right kidney stroma of bone marrow lumbar subsegment of spinal cord left lobe of liver human kidney jejunum blastocyst duodenum proximal tubule More reference expression data BioGPS More reference expression data
Gene ontology Molecular function inositol 1,3,4,5 tetrakisphosphate binding protein-macromolecule adaptor activity phosphatidylinositol-4,5-bisphosphate binding protein binding phosphatidylinositol-3,4,5-trisphosphate binding metal ion binding GTPase activator activity phosphatidylinositol-3,4-bisphosphate binding phosphatidylinositol bisphosphate binding Cellular component cytoplasm plasma membrane mitochondrial envelope membrane Biological process heart development positive regulation of GTPase activity Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55803 216991 Ensembl ENSG00000184060 ENSMUSG00000020709 UniProt Q9NPF8 Q8R2V5 RefSeq (mRNA) NM_001346712 NM_001346714 NM_001346716 NM_018404 NM_172133 RefSeq (protein) NP_001333641 NP_001333643 NP_001333645 NP_060874 NP_742145 Location (UCSC) Chr 17: 30.91 – 30.96 Mb Chr 11: 80.15 – 80.18 Mb PubMed search [3] [4]
Wikidata
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