ADM2

ADM2 is a protein that in humans is encoded by the ADM2 gene.^[5][6]

ADM2
Identifiers
Aliases	ADM2, AM2, dJ579N16.4, adrenomedullin 2
External IDs	OMIM: 608682; MGI: 2675256; HomoloGene: 49801; GeneCards: ADM2; OMA:ADM2 - orthologs
Gene location (Human) Chr. Chromosome 22 (human)[1] Band 22q13.33 Start 50,481,543 bp[1] End 50,486,440 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15|15 E3 Start 89,206,923 bp[2] End 89,208,934 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in body of pancreas left lobe of thyroid gland stromal cell of endometrium right lobe of thyroid gland duodenum lymph node renal cortex salivary gland bone marrow cells human kidney Top expressed in zygote secondary oocyte primary oocyte morula embryo embryo calvaria right kidney epiblast blastocyst More reference expression data BioGPS More reference expression data
Gene ontology Molecular function hormone activity protein-containing complex binding Cellular component extracellular region intracellular anatomical structure Biological process digestion protein phosphorylation positive regulation of gene expression adenylate cyclase-activating G protein-coupled receptor signaling pathway angiogenesis feeding behavior positive regulation of angiogenesis negative regulation of blood pressure regulation of signaling receptor activity G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79924 223780 Ensembl ENSG00000128165 ENSMUSG00000054136 UniProt Q7Z4H4 Q7TNK8 RefSeq (mRNA) NM_024866 NM_001253845 NM_001369882 NM_182928 RefSeq (protein) NP_001240774 NP_001356811 NP_891558 Location (UCSC) Chr 22: 50.48 – 50.49 Mb Chr 15: 89.21 – 89.21 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

ADM2 belongs to a family of calcitonin (MIM 114130)-related peptide hormones important for regulating diverse physiologic functions and the chemical composition of fluids and tissues.[supplied by OMIM]^[6]