AKAP8L

A-kinase anchor protein 8-like is a protein that in humans is encoded by the AKAP8L gene.^[5][6][7]

AKAP8L
Identifiers
Aliases	AKAP8L, HA95, HAP95, NAKAP, NAKAP95, A-kinase anchoring protein 8 like
External IDs	OMIM: 609475; MGI: 1860606; HomoloGene: 8658; GeneCards: AKAP8L; OMA:AKAP8L - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19p13.12 Start 15,380,050 bp[1] End 15,419,141 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17|17 B1 Start 32,321,424 bp[2] End 32,350,607 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right hemisphere of cerebellum right uterine tube right lobe of thyroid gland anterior pituitary left lobe of thyroid gland sural nerve right testis left testis right adrenal cortex gastric mucosa Top expressed in superior frontal gyrus neural layer of retina primary visual cortex entorhinal cortex spermatid cerebellar cortex muscle of thigh perirhinal cortex central gray substance of midbrain spermatocyte More reference expression data BioGPS More reference expression data
Gene ontology Molecular function metal ion binding lamin binding histone deacetylase binding DEAD/H-box RNA helicase binding DNA binding protein binding RNA binding protein kinase A regulatory subunit binding Cellular component nuclear matrix chromatin nuclear speck PML body nucleus cytoplasm ribonucleoprotein complex Biological process positive regulation of histone deacetylation nuclear membrane disassembly regulation of mRNA export from nucleus mitotic chromosome condensation cell cycle G2/M phase transition positive regulation of transcription by RNA polymerase II transcription, DNA-templated regulation of transcription, DNA-templated RNA splicing mRNA processing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 26993 54194 Ensembl ENSG00000011243 ENSMUSG00000002625 UniProt Q9ULX6 Q9R0L7 RefSeq (mRNA) NM_001291478 NM_014371 NM_017476 RefSeq (protein) NP_001278407 NP_055186 n/a Location (UCSC) Chr 19: 15.38 – 15.42 Mb Chr 17: 32.32 – 32.35 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

AKAP8L has been shown to interact with:

• DHX9,^[5][8] and
• Thymopoietin.^[9][10]