ALG10B

Alpha-1,2-glucosyltransferase ALG10-B is an enzyme that in humans is encoded by the ALG10B gene.^[5] It is a member of the Dolichyl-P-Glc:Glc2Man9GlcNAc2-PP-dolichol alpha-1,2-glucosyltransferase class of enzymes. It has ubiquitous expression in 27 tissues.^[6]

ALG10B
Identifiers
Aliases	ALG10B, ALG10, KCR1, alpha-1,2-glucosyltransferase, ALG10 alpha-1,2-glucosyltransferase B
External IDs	OMIM: 603313; MGI: 2146159; HomoloGene: 107128; GeneCards: ALG10B; OMA:ALG10B - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q12 Start 38,316,762 bp[1] End 38,329,721 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15|15 E3 Start 90,108,514 bp[2] End 90,117,674 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon retinal pigment epithelium tibia testicle germinal epithelium gonad ventricular zone ganglionic eminence mucosa of paranasal sinus endometrium Top expressed in hand secondary oocyte superior cervical ganglion primary oocyte atrioventricular valve otolith organ trigeminal ganglion utricle endocardial cushion medial ganglionic eminence More reference expression data BioGPS n/a
Gene ontology Molecular function dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity glycosyltransferase activity transferase activity dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity Cellular component integral component of membrane plasma membrane endoplasmic reticulum membrane membrane endoplasmic reticulum Biological process dolichol-linked oligosaccharide biosynthetic process protein glycosylation positive regulation of protein glycosylation positive regulation of inward rectifier potassium channel activity Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 144245 380959 Ensembl ENSG00000175548 ENSMUSG00000075470 UniProt Q5I7T1 Q3UGP8 RefSeq (mRNA) NM_001013620 NM_001308340 NM_001033441 RefSeq (protein) NP_001013642 NP_001295269 NP_001028613 Location (UCSC) Chr 12: 38.32 – 38.33 Mb Chr 15: 90.11 – 90.12 Mb PubMed search [3] [4]
Wikidata
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