ANKRD23

Ankyrin repeat domain-containing protein 23 is a protein that in humans is encoded by the ANKRD23 gene.^[5][6]

ANKRD23
Identifiers
Aliases	ANKRD23, DARP, MARP3, ankyrin repeat domain 23
External IDs	OMIM: 610736; MGI: 1925571; HomoloGene: 14025; GeneCards: ANKRD23; OMA:ANKRD23 - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q11.2 Start 96,824,526 bp[1] End 96,857,934 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 B Start 36,569,269 bp[2] End 36,575,964 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in muscle of thigh gastrocnemius muscle sural nerve tibialis anterior muscle skeletal muscle tissue quadriceps femoris muscle vastus lateralis muscle right uterine tube apex of heart biceps brachii Top expressed in quadriceps femoris muscle muscle tissue muscle of thigh skeletal muscle tissue esophagus zone of skin lip heart adrenal gland neural layer of retina More reference expression data BioGPS n/a
Gene ontology Molecular function titin binding Cellular component myofibril nucleus intercalated disc nucleoplasm actin cytoskeleton cytosol Biological process response to mechanical stimulus Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 200539 78321 Ensembl ENSG00000163126 ENSMUSG00000067653 UniProt Q86SG2 Q812A3 RefSeq (mRNA) NM_144994 NM_153502 NM_001310521 RefSeq (protein) NP_659431 NP_001297450 NP_705722 Location (UCSC) Chr 2: 96.82 – 96.86 Mb Chr 1: 36.57 – 36.58 Mb PubMed search [3] [4]
Wikidata
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This gene is a member of the muscle ankyrin repeat protein (MARP) family and encodes a protein with four tandem ankyrin-like repeats. The protein is localized to the nucleus, functioning as a transcriptional regulator. Expression of this protein is induced during recovery following starvation.^[6]

Interactions

ANKRD23 has been shown to interact with Titin^[7] and MYPN.^[7]