ANKRD27

Ankyrin repeat domain-containing protein 27 is a protein that in humans is encoded by the ANKRD27 gene.^[5][6][7]

ANKRD27
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4B93, 4CYM, 4CZ2
Identifiers
Aliases	ANKRD27, VARP, PP12899, ankyrin repeat domain 27
External IDs	MGI: 2444103; HomoloGene: 12956; GeneCards: ANKRD27; OMA:ANKRD27 - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19q13.11 Start 32,597,006 bp[1] End 32,676,597 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 B2 Start 35,285,669 bp[2] End 35,338,651 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Epithelium of choroid plexus amniotic fluid skin of thigh palpebral conjunctiva Brodmann area 23 tail of epididymis seminal vesicula epithelium of nasopharynx lower lobe of lung testicle Top expressed in neural layer of retina ascending aorta lacrimal gland zygote aortic valve tail of embryo lumbar spinal ganglion parotid gland epiblast oocyte More reference expression data BioGPS More reference expression data
Gene ontology Molecular function GTPase activator activity guanyl-nucleotide exchange factor activity protein binding SNARE binding Cellular component endosome late endosome membrane melanosome plasma membrane transport vesicle tubular endosome early endosome lysosome cytoplasmic vesicle membrane cytoplasmic vesicle cytosol neuron projection Biological process negative regulation of SNARE complex assembly early endosome to late endosome transport positive regulation of dendrite morphogenesis endosome to melanosome transport protein transport positive regulation of GTPase activity neuron projection morphogenesis transport regulation of molecular function positive regulation of neuron projection development Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 84079 245886 Ensembl ENSG00000105186 ENSMUSG00000034867 UniProt Q96NW4 Q3UMR0 RefSeq (mRNA) NM_032139 NM_145633 NM_178263 NM_001358876 RefSeq (protein) NP_115515 NP_663608 NP_839994 NP_001345805 Location (UCSC) Chr 19: 32.6 – 32.68 Mb Chr 7: 35.29 – 35.34 Mb PubMed search [3] [4]
Wikidata
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