AP-238

AP-238 is an opioid designer drug related to drugs such as azaprocin and bucinnazine, with around the same potency as morphine.^[2] It was first discovered in Italy in the 1960s but was never marketed,^[3] subsequently appearing on the illicit market around 2020 and being detected in both Slovenia and the USA.^[4][5]

AP-238

Legal status
Legal status	UK: Under Psychoactive Substances Act US: The DEA is not of the opinion that AP-237 and derivatives are Controlled Substances, or analogues thereof. [1]
Identifiers
IUPAC name 1-[(2R,6S)-2,6-dimethyl-4-[(E)-3-phenylprop-2-enyl]piperazin-1-yl]propan-1-one
CAS Number	(racemic) 4204-01-7 (racemic) 140924-11-4 (2R,6S enantiomer)
PubChem CID	124389619
ChemSpider	4941886
UNII	N26WML8AR7
Chemical and physical data
Formula	C18H26N2O
Molar mass	286.419 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCC(=O)N1[C@@H](CN(C[C@@H]1C)C/C=C/C2=CC=CC=C2)C
InChI InChI=1S/C18H26N2O/c1-4-18(21)20-15(2)13-19(14-16(20)3)12-8-11-17-9-6-5-7-10-17/h5-11,15-16H,4,12-14H2,1-3H3/b11-8+/t15-,16+ Key:JELNWDOXWGBBLO-QJBCGIKSSA-N

See also

• 2F-Viminol
• Diphenpipenol
• Dipyanone
• Etodesnitazene
• MT-45
• Nortilidine
• O-AMKD
• O-DSMT
• Piperidylthiambutene
• SHR9352