AP1AR

AP-1 complex-associated regulatory protein (Gamma1-adaptin brefeldin A resistance protein) is a protein that in humans is encoded by the AP1AR gene.^[5][6]

AP1AR
Identifiers
Aliases	AP1AR, 2C18, C4orf16, GBAR, gamma-BAR, PRO0971, adaptor related protein complex 1 associated regulatory protein
External IDs	OMIM: 610851; MGI: 2384822; HomoloGene: 10236; GeneCards: AP1AR; OMA:AP1AR - orthologs
Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4q25 Start 112,231,740 bp[1] End 112,273,110 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 G2 Start 127,600,656 bp[2] End 127,631,172 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon ganglionic eminence jejunal mucosa rectum monocyte testicle ventricular zone mucosa of sigmoid colon stromal cell of endometrium islet of Langerhans Top expressed in trigeminal ganglion epithelium of small intestine conjunctival fornix vestibular membrane of cochlear duct dorsal striatum Ileal epithelium primitive streak corneal stroma entorhinal cortex vestibular sensory epithelium More reference expression data BioGPS More reference expression data
Gene ontology Molecular function kinesin binding AP-1 adaptor complex binding Cellular component late endosome Golgi apparatus early endosome transport vesicle cytosol endosome Biological process protein transport negative regulation of cell motility negative regulation of substrate adhesion-dependent cell spreading regulation of Arp2/3 complex-mediated actin nucleation negative regulation of receptor recycling vesicle targeting, trans-Golgi to endosome Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55435 211556 Ensembl ENSG00000138660 ENSMUSG00000074238 UniProt Q63HQ0 n/a RefSeq (mRNA) NM_001128426 NM_018569 NM_145964 NM_001346718 RefSeq (protein) NP_001121898 NP_061039 n/a Location (UCSC) Chr 4: 112.23 – 112.27 Mb Chr 3: 127.6 – 127.63 Mb PubMed search [3] [4]
Wikidata
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