APBB1IP

Amyloid beta A4 precursor protein-binding family B member 1-interacting protein (APBB1IP), also known as APBB1-interacting protein 1 or Rap1-GTP-interacting adapter molecule (RIAM) is a protein that in humans is encoded by the APBB1IP gene.^[5][6][7]

APBB1IP
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2MWN, 3ZDL
Identifiers
Aliases	APBB1IP, amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein, INAG1, PREL1, RARP1, RIAM, amyloid beta precursor protein binding family B member 1 interacting protein
External IDs	OMIM: 609036; MGI: 1861354; HomoloGene: 32434; GeneCards: APBB1IP; OMA:APBB1IP - orthologs
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10p12.1 Start 26,438,341 bp[1] End 26,567,803 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 A3 Start 22,664,106 bp[2] End 22,765,665 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in blood monocyte granulocyte inferior ganglion of vagus nerve trabecular bone spleen synovial joint lactiferous duct lymph node superficial temporal artery Top expressed in granulocyte thymus ankle joint lactiferous gland spleen mesenteric lymph nodes bone marrow blood molar pharynx More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding Cellular component cytoplasm cell junction cell projection T cell receptor complex cytoskeleton membrane focal adhesion lamellipodium cytosol plasma membrane Biological process T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell signal transduction positive regulation of cell adhesion Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 54518 54519 Ensembl ENSG00000077420 ENSMUSG00000026786 UniProt Q7Z5R6 Q8R5A3 RefSeq (mRNA) NM_019043 NM_019456 RefSeq (protein) NP_061916 NP_062329 Location (UCSC) Chr 10: 26.44 – 26.57 Mb Chr 2: 22.66 – 22.77 Mb PubMed search [3] [4]
Wikidata
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