APOBEC2

Probable C->U-editing enzyme APOBEC-2 is a protein that in humans is encoded by the APOBEC2 gene.^[5][6]

APOBEC2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2NYT
Identifiers
Aliases	APOBEC2, ARCD1, ARP1, apolipoprotein B mRNA editing enzyme catalytic subunit 2
External IDs	OMIM: 604797; MGI: 1343178; HomoloGene: 4941; GeneCards: APOBEC2; OMA:APOBEC2 - orthologs
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6p21.1 Start 41,053,202 bp[1] End 41,064,891 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17 C|17 24.02 cM Start 48,726,259 bp[2] End 48,739,958 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Skeletal muscle tissue of rectus abdominis biceps brachii triceps brachii muscle Skeletal muscle tissue of biceps brachii muscle of thigh glutes thoracic diaphragm vastus lateralis muscle deltoid muscle apex of heart Top expressed in quadriceps femoris muscle muscle of thigh zone of skin esophagus skeletal muscle tissue heart lip epithelium of urethra ejaculatory duct epithelium of male urethra More reference expression data BioGPS More reference expression data
Gene ontology Molecular function hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines zinc ion binding catalytic activity hydrolase activity metal ion binding RNA binding cytidine deaminase activity identical protein binding Cellular component nucleus cytoplasm Biological process DNA demethylation mRNA processing mRNA modification cytidine deamination cytidine to uridine editing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10930 11811 Ensembl ENSG00000124701 ENSMUSG00000040694 UniProt Q9Y235 Q9WV35 RefSeq (mRNA) NM_006789 NM_009694 RefSeq (protein) NP_006780 NP_033824 Location (UCSC) Chr 6: 41.05 – 41.06 Mb Chr 17: 48.73 – 48.74 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse