APOF

Apolipoprotein F is a protein that in humans is encoded for by the APOF gene.^[5][6] The product of this gene is one of the minor apolipoproteins found in plasma. This protein forms complexes with lipoproteins and may be involved in transport and/or esterification of cholesterol.^[6]

APOF
Identifiers
Aliases	APOF, Apo-F, LTIP, apolipoprotein F
External IDs	OMIM: 107760; MGI: 104539; HomoloGene: 48030; GeneCards: APOF; OMA:APOF - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q13.3 Start 56,360,568 bp[1] End 56,362,857 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10 D3|10 76.5 cM Start 128,103,866 bp[2] End 128,106,022 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of liver granulocyte islet of Langerhans prostate kidney blood head human musculoskeletal system muscular system muscle Top expressed in left lobe of liver submandibular gland gallbladder seminal vesicula sexually immature organism fetal liver hematopoietic progenitor cell human fetus abdominal wall stomach ureter More reference expression data BioGPS More reference expression data
Gene ontology Molecular function cholesterol binding signaling receptor binding lipid transporter activity Cellular component low-density lipoprotein particle high-density lipoprotein particle extracellular region extracellular space Biological process steroid metabolic process lipid transport cholesterol metabolic process lipid metabolism Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 319 103161 Ensembl ENSG00000175336 ENSMUSG00000047631 UniProt Q13790 Q91V80 RefSeq (mRNA) NM_001638 NM_133997 RefSeq (protein) NP_001629 NP_598758 Location (UCSC) Chr 12: 56.36 – 56.36 Mb Chr 10: 128.1 – 128.11 Mb PubMed search [3] [4]
Wikidata
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Apolipoprotein F
Identifiers
Symbol	APOF
Pfam	PF15148
InterPro	IPR026114
Available protein structures: Pfam   structures / ECOD   PDB RCSB PDB; PDBe; PDBj PDBsum structure summary